Sertraline is an SSRI antidepressant. Its use in bodybuilding is not for performance or muscle growth, but to manage mental health.

The primary reason for its use is to counteract mood-related side effects, specifically from steroid cycles that include compounds like Trenbolone or high doses of other androgens, which are notorious for causing:

· Severe irritability (“Tren Rage”)
· Anxiety
· Depression
· Mood swings

In this context, sertraline is used as a protective measure to stabilize mood and make intense cycles more manageable.